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IRF2BP2 3′UTR Polymorphism Increases Coronary Artery Calcification in Men
Interferon regulatory factor 2 binding protein 2 (IRF2BP2) suppresses the innate inflammatory response of macrophages. A 9-nucleotide deletion (rs3045215) in the 3′ untranslated region (3′-UTR) of human IRF2BP2 mRNA confers risk of coronary artery disease (CAD) in the Ottawa Heart Genomics Study (OH...
Autores principales: | Vilmundarson, Ragnar O., Duong, An, Soheili, Fariborz, Chen, Hsiao-Huei, Stewart, Alexandre F. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573268/ https://www.ncbi.nlm.nih.gov/pubmed/34760935 http://dx.doi.org/10.3389/fcvm.2021.687645 |
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