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Cellular Size, Gap Junctions, and Sodium Channel Properties Govern Developmental Changes in Cardiac Conduction

Electrical conduction in cardiac ventricular tissue is regulated via sodium (Na(+)) channels and gap junctions (GJs). We and others have recently shown that Na(+)channels preferentially localize at the site of cell-cell junctions, the intercalated disc (ID), in adult cardiac tissue, facilitating cou...

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Detalles Bibliográficos
Autores principales: Nowak, Madison B., Veeraraghavan, Rengasayee, Poelzing, Steven, Weinberg, Seth H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573326/
https://www.ncbi.nlm.nih.gov/pubmed/34759834
http://dx.doi.org/10.3389/fphys.2021.731025