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Tlr2/4 Double Knockout Attenuates the Degeneration of Primary Auditory Neurons: Potential Mechanisms From Transcriptomic Perspectives

The transcriptomic landscape of mice with primary auditory neurons degeneration (PAND) indicates key pathways in its pathogenesis, including complement cascades, immune responses, tumor necrosis factor (TNF) signaling pathway, and cytokine-cytokine receptor interaction. Toll-like receptors (TLRs) ar...

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Detalles Bibliográficos
Autores principales: Wang, Quan, Shen, Yilin, Pan, Yi, Chen, Kaili, Ding, Rui, Zou, Tianyuan, Zhang, Andi, Guo, Dongye, Ji, Peilin, Fan, Cui, Mei, Ling, Hu, Haixia, Ye, Bin, Xiang, Mingliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573328/
https://www.ncbi.nlm.nih.gov/pubmed/34760891
http://dx.doi.org/10.3389/fcell.2021.750271