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Concentration-Dependent Decitabine Effects on Primary NK Cells Viability, Phenotype, and Function in the Absence of Obvious NK Cells Proliferation–Original Article

Acute myeloid leukemia (AML) cells can evade innate immune killing by modulating natural killer (NK) cells receptors and their cognate ligands in tumor cells, thus it may be possible to restore proper expression of immune receptors or ligands with immune sensitive drugs. Decitabine, as a hypomethyla...

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Detalles Bibliográficos
Autores principales: Li, Xiang, Zhang, Min, Cai, Sisi, Wu, Yaohui, You, Yong, Wang, Xianghong, Wang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573336/
https://www.ncbi.nlm.nih.gov/pubmed/34759824
http://dx.doi.org/10.3389/fphar.2021.755662