Cargando…

STAT3 and IL-6 Contribute to Corticosteroid Resistance in an OVA and Ozone-induced Asthma Model with Neutrophil Infiltration

Exposure to high levels of ozone contributes to insensitivity to glucocorticoids in asthma treatment, but the underlying mechanisms are not known. We built two asthma models: a “T2-high” asthma model was established by ovalbumin (OVA) sensitization/challenge and OVA sensitization/challenge combined...

Descripción completa

Detalles Bibliográficos
Autores principales: Xue, Yishu, Zhou, Yan, Bao, Wuping, Fu, Qiang, Hao, Huijuan, Han, Lei, Zhang, Xue, Tian, Xue, Zhang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573338/
https://www.ncbi.nlm.nih.gov/pubmed/34760922
http://dx.doi.org/10.3389/fmolb.2021.717962