Klotho upregulates the interaction between RANK and TRAF6 to facilitate RANKL-induced osteoclastogenesis via the NF-κB signaling pathway

BACKGROUND: α-Klotho (Klotho) plays a wide range of roles in pathophysiological processes, such as low-turnover osteoporosis observed in klotho mutant mice (kl/kl mice). However, the precise function and underlying mechanism of klotho during osteoclastogenesis are not fully understood. Here, we inve...

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Detalles Bibliográficos
Autores principales: Yu, Tao, Dou, Ce, Lu, Yanzhu, Duan, Lianli, Tan, Jiulin, Li, Jianmei, Kang, Fei, Dong, Shiwu, Bai, Yun, Xu, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573428/
https://www.ncbi.nlm.nih.gov/pubmed/34805361
http://dx.doi.org/10.21037/atm-21-4332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573428/
https://www.ncbi.nlm.nih.gov/pubmed/34805361
http://dx.doi.org/10.21037/atm-21-4332

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