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Successful targeting of the NRG1 fusion reveals durable response to afatinib in lung adenocarcinoma: a case report
The treatments for advanced non-small cell lung cancer (NSCLC) patients have been improved by developing tyrosine kinase inhibitors (TKIs) as targeted therapies. Oncogenic gene fusions resulting from structural DNA rearrangements have been proposed as a unique class of oncogenic drivers and therapeu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573434/ https://www.ncbi.nlm.nih.gov/pubmed/34805369 http://dx.doi.org/10.21037/atm-21-3923 |