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Inhibiting parasite proliferation using a rationally designed anti‐tubulin agent

Infectious diseases caused by apicomplexan parasites remain a global public health threat. The presence of multiple ligand‐binding sites in tubulin makes this protein an attractive target for anti‐parasite drug discovery. However, despite remarkable successes as anti‐cancer agents, the rational deve...

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Detalles Bibliográficos
Autores principales: Gaillard, Natacha, Sharma, Ashwani, Abbaali, Izra, Liu, Tianyang, Shilliday, Fiona, Cook, Alexander D, Ehrhard, Valentin, Bangera, Mamata, Roberts, Anthony J, Moores, Carolyn A, Morrissette, Naomi, Steinmetz, Michel O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573600/
https://www.ncbi.nlm.nih.gov/pubmed/34661376
http://dx.doi.org/10.15252/emmm.202013818