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Normal variation of the gut microbiota affects hepatic cytochrome P450 activity in mice

Several studies revealed that substantial artificial changes in the gut microbiota resulted in modification of hepatic cytochrome P450 3a (Cyp3a) in mice. Consequently, we hypothesized that “normal” variation of the gut microbiota might also alter hepatic Cyp activity and lead to individual differen...

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Detalles Bibliográficos
Autores principales: Togao, Masao, Tajima, Shinnosuke, Kurakawa, Takashi, Wagai, Gaku, Otsuka, Jun, Kado, Shoichi, Kawakami, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573722/
https://www.ncbi.nlm.nih.gov/pubmed/34747570
http://dx.doi.org/10.1002/prp2.893