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STAT5 is activated in macrophages by breast cancer cell-derived factors and regulates macrophage function in the tumor microenvironment

BACKGROUND: In breast cancer, complex interactions between tumor cells and cells within the surrounding stroma, such as macrophages, are critical for tumor growth, progression, and therapeutic response. Recent studies have highlighted the complex nature and heterogeneous populations of macrophages a...

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Detalles Bibliográficos
Autores principales: Jesser, Emily A., Brady, Nicholas J., Huggins, Danielle N., Witschen, Patrice M., O’Connor, Christine H., Schwertfeger, Kathryn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573892/
https://www.ncbi.nlm.nih.gov/pubmed/34743736
http://dx.doi.org/10.1186/s13058-021-01481-0