Cargando…
STAT5 is activated in macrophages by breast cancer cell-derived factors and regulates macrophage function in the tumor microenvironment
BACKGROUND: In breast cancer, complex interactions between tumor cells and cells within the surrounding stroma, such as macrophages, are critical for tumor growth, progression, and therapeutic response. Recent studies have highlighted the complex nature and heterogeneous populations of macrophages a...
Autores principales: | Jesser, Emily A., Brady, Nicholas J., Huggins, Danielle N., Witschen, Patrice M., O’Connor, Christine H., Schwertfeger, Kathryn L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573892/ https://www.ncbi.nlm.nih.gov/pubmed/34743736 http://dx.doi.org/10.1186/s13058-021-01481-0 |
Ejemplares similares
-
Macrophages: Regulators of the Inflammatory Microenvironment during Mammary Gland Development and Breast Cancer
por: Brady, Nicholas J., et al.
Publicado: (2016) -
Tissue-resident macrophages promote extracellular matrix homeostasis in the mammary gland stroma of nulliparous mice
por: Wang, Ying, et al.
Publicado: (2020) -
STAT5 deletion in macrophages alters ductal elongation and branching during mammary gland development
por: Brady, Nicholas J., et al.
Publicado: (2017) -
Tumor Cell Associated Hyaluronan-CD44 Signaling Promotes Pro-Tumor Inflammation in Breast Cancer
por: Witschen, Patrice M., et al.
Publicado: (2020) -
Erratum: Witschen, P.M., et al. Tumor Cell Associated Hyaluronan-CD44 Signaling Promotes Pro-Tumor Inflammation in Breast Cancer. Cancers 2020, 12, 1325
por: Witschen, Patrice M., et al.
Publicado: (2020)