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Dimethyl itaconate alleviates the pyroptosis of macrophages through oxidative stress

Macrophages are involved in the pathophysiology of many diseases as critical cells of the innate immune system. Pyroptosis is a form of macrophage death that induces cytokinesis of phagocytic substances in the macrophages, thereby defending against infection. Dimethyl itaconate (DI) is an analog of...

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Detalles Bibliográficos
Autores principales: Huang, Shan-Shan, Guo, Dong-Yang, Jia, Bing-Bing, Cai, Guo-Long, Yan, Jing, Lu, Yan, Yang, Zhou-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573905/
https://www.ncbi.nlm.nih.gov/pubmed/34749650
http://dx.doi.org/10.1186/s12865-021-00463-3