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Starvation induced autophagy promotes the progression of bladder cancer by LDHA mediated metabolic reprogramming

BACKGROUND: Aberrant autophagy and preternatural elevated glycolysis are prevalent in bladder cancer (BLCA) and are both related to malignant progression. However, the regulatory relationship between autophagy and glycolytic metabolism remains largely unknown. We imitated starvation conditions in th...

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Detalles Bibliográficos
Autores principales: Li, Tinghao, Tong, Hang, Yin, Hubin, Luo, Yi, Zhu, Junlong, Qin, Zijia, Yin, Siwen, He, Weiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573950/
https://www.ncbi.nlm.nih.gov/pubmed/34743698
http://dx.doi.org/10.1186/s12935-021-02303-1