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Establishment of multiplex RT-PCR to detect fusion genes for the diagnosis of Ewing sarcoma
BACKGROUND: Detection of the tumor-specific EWSR1/FUS-ETS fusion gene is essential to diagnose Ewing sarcoma. Reverse transcription–polymerase chain reaction (RT–PCR) and fluorescence in situ hybridization are commonly used to detect the fusion gene, and assays using next-generation sequencing have...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573982/ https://www.ncbi.nlm.nih.gov/pubmed/34749732 http://dx.doi.org/10.1186/s13000-021-01164-6 |