Establishment of multiplex RT-PCR to detect fusion genes for the diagnosis of Ewing sarcoma

BACKGROUND: Detection of the tumor-specific EWSR1/FUS-ETS fusion gene is essential to diagnose Ewing sarcoma. Reverse transcription–polymerase chain reaction (RT–PCR) and fluorescence in situ hybridization are commonly used to detect the fusion gene, and assays using next-generation sequencing have...

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Detalles Bibliográficos
Autores principales: Ueno-Yokohata, Hitomi, Okita, Hajime, Nakasato, Keiko, Kiyotani, Chikako, Kato, Motohiro, Matsumoto, Kimikazu, Kiyokawa, Nobutaka, Nakazawa, Atsuko, Yoshioka, Takako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573982/
https://www.ncbi.nlm.nih.gov/pubmed/34749732
http://dx.doi.org/10.1186/s13000-021-01164-6

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