TAD-like single-cell domain structures exist on both active and inactive X chromosomes and persist under epigenetic perturbations

BACKGROUND: Topologically associating domains (TADs) are important building blocks of three-dimensional genome architectures. The formation of TADs has been shown to depend on cohesin in a loop-extrusion mechanism. Recently, advances in an image-based spatial genomics technique known as chromatin tr...

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Detalles Bibliográficos
Autores principales: Cheng, Yubao, Liu, Miao, Hu, Mengwei, Wang, Siyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8574027/
https://www.ncbi.nlm.nih.gov/pubmed/34749781
http://dx.doi.org/10.1186/s13059-021-02523-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8574027/
https://www.ncbi.nlm.nih.gov/pubmed/34749781
http://dx.doi.org/10.1186/s13059-021-02523-8

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