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Polygenic risk score across distinct colorectal cancer screening outcomes: from premalignant polyps to colorectal cancer

BACKGROUND: Different risk-based colorectal cancer (CRC) screening strategies, such as the use of polygenic risk scores (PRS), have been evaluated to improve effectiveness of these programs. However, few studies have previously assessed its usefulness in a fecal immunochemical test (FIT)-based scree...

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Detalles Bibliográficos
Autores principales: Obón-Santacana, Mireia, Díez-Villanueva, Anna, Alonso, Maria Henar, Ibáñez-Sanz, Gemma, Guinó, Elisabet, López, Ana, Rodríguez-Alonso, Lorena, Mata, Alfredo, García-Rodríguez, Ana, Palomo, Andrés García, Molina, Antonio J., Garcia, Montse, Binefa, Gemma, Martín, Vicente, Moreno, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8574048/
https://www.ncbi.nlm.nih.gov/pubmed/34743725
http://dx.doi.org/10.1186/s12916-021-02134-x