Gold-catalysed asymmetric net addition of unactivated propargylic C–H bonds to tethered aldehydes

The asymmetric one-step net addition of unactivated propargylic C-H bond to aldehyde leads to an atom-economic construction of versatile chiral propargylic alcohols but has not been realized previously. Here we show its implementation in an intramolecular manner under mild reaction conditions. Via c...

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Detalles Bibliográficos
Autores principales: Li, Ting, Cheng, Xinpeng, Qian, Pengcheng, Zhang, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8574197/
https://www.ncbi.nlm.nih.gov/pubmed/34755042
http://dx.doi.org/10.1038/s41929-020-00569-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8574197/
https://www.ncbi.nlm.nih.gov/pubmed/34755042
http://dx.doi.org/10.1038/s41929-020-00569-8

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