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Chrom-Lasso: a lasso regression-based model to detect functional interactions using Hi-C data
Hi-C is a genome-wide assay based on Chromosome Conformation Capture and high-throughput sequencing to decipher 3D chromatin organization in the nucleus. However, computational methods to detect functional interactions utilizing Hi-C data face challenges including the correction for various sources...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8574949/ https://www.ncbi.nlm.nih.gov/pubmed/34013331 http://dx.doi.org/10.1093/bib/bbab181 |