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Chrom-Lasso: a lasso regression-based model to detect functional interactions using Hi-C data

Hi-C is a genome-wide assay based on Chromosome Conformation Capture and high-throughput sequencing to decipher 3D chromatin organization in the nucleus. However, computational methods to detect functional interactions utilizing Hi-C data face challenges including the correction for various sources...

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Detalles Bibliográficos
Autores principales: Lu, Jingzhe, Wang, Xu, Sun, Keyong, Lan, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8574949/
https://www.ncbi.nlm.nih.gov/pubmed/34013331
http://dx.doi.org/10.1093/bib/bbab181