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A comparison of metabolic labeling and statistical methods to infer genome-wide dynamics of RNA turnover

Metabolic labeling of newly transcribed RNAs coupled with RNA-seq is being increasingly used for genome-wide analysis of RNA dynamics. Methods including standard biochemical enrichment and recent nucleotide conversion protocols each require special experimental and computational treatment. Despite t...

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Detalles Bibliográficos
Autores principales: Boileau, Etienne, Altmüller, Janine, Naarmann-de Vries, Isabel S, Dieterich, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8574959/
https://www.ncbi.nlm.nih.gov/pubmed/34228787
http://dx.doi.org/10.1093/bib/bbab219