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COSMIC Cancer Gene Census 3D database: understanding the impacts of mutations on cancer targets

Mutations in hallmark genes are believed to be the main drivers of cancer progression. These mutations are reported in the Catalogue of Somatic Mutations in Cancer (COSMIC). Structural appreciation of where these mutations appear, in protein–protein interfaces, active sites or deoxyribonucleic acid...

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Detalles Bibliográficos
Autores principales: Alsulami, Ali F, Torres, Pedro H M, Moghul, Ismail, Arif, Sheikh Mohammed, Chaplin, Amanda K, Vedithi, Sundeep Chaitanya, Blundell, Tom L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8574963/
https://www.ncbi.nlm.nih.gov/pubmed/34137435
http://dx.doi.org/10.1093/bib/bbab220