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Network-guided identification of cancer-selective combinatorial therapies in ovarian cancer

Each patient’s cancer consists of multiple cell subpopulations that are inherently heterogeneous and may develop differing phenotypes such as drug sensitivity or resistance. A personalized treatment regimen should therefore target multiple oncoproteins in the cancer cell populations that are driving...

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Detalles Bibliográficos
Autores principales: He, Liye, Bulanova, Daria, Oikkonen, Jaana, Häkkinen, Antti, Zhang, Kaiyang, Zheng, Shuyu, Wang, Wenyu, Erkan, Erdogan Pekcan, Carpén, Olli, Joutsiniemi, Titta, Hietanen, Sakari, Hynninen, Johanna, Huhtinen, Kaisa, Hautaniemi, Sampsa, Vähärautio, Anna, Tang, Jing, Wennerberg, Krister, Aittokallio, Tero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8574973/
https://www.ncbi.nlm.nih.gov/pubmed/34343245
http://dx.doi.org/10.1093/bib/bbab272