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Blood-thirsty: S1PR5 and T(RM)

In this elegant study, Evrard et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20210116) find that sphingosine 1-phosphate receptor 5 (S1PR5) powerfully impairs tissue-resident memory T cell (T(RM)) formation, and that tissue-derived TGF-β limits S1pr5 expression by infiltrating T cells.

Detalles Bibliográficos
Autores principales: Hallisey, Victoria M., Schwab, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8574975/
https://www.ncbi.nlm.nih.gov/pubmed/34714328
http://dx.doi.org/10.1084/jem.20211971