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Blood-thirsty: S1PR5 and T(RM)
In this elegant study, Evrard et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20210116) find that sphingosine 1-phosphate receptor 5 (S1PR5) powerfully impairs tissue-resident memory T cell (T(RM)) formation, and that tissue-derived TGF-β limits S1pr5 expression by infiltrating T cells.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8574975/ https://www.ncbi.nlm.nih.gov/pubmed/34714328 http://dx.doi.org/10.1084/jem.20211971 |
| Sumario: | In this elegant study, Evrard et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20210116) find that sphingosine 1-phosphate receptor 5 (S1PR5) powerfully impairs tissue-resident memory T cell (T(RM)) formation, and that tissue-derived TGF-β limits S1pr5 expression by infiltrating T cells. |
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