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Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer

Immune checkpoint blockade (ICB) has improved outcomes in some cancers. A major limitation of ICB is that most patients fail to respond, which is partly attributable to immunosuppression. Obesity appears to improve immune checkpoint therapies in some cancers, but impacts on breast cancer (BC) remain...

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Detalles Bibliográficos
Autores principales: Pingili, Ajeeth K., Chaib, Mehdi, Sipe, Laura M., Miller, Emily J., Teng, Bin, Sharma, Rahul, Yarbro, Johnathan R., Asemota, Sarah, Al Abdallah, Qusai, Mims, Tahliyah S., Marion, Tony N., Daria, Deidre, Sekhri, Radhika, Hamilton, Alina M., Troester, Melissa A., Jo, Heejoon, Choi, Hyo Young, Hayes, D. Neil, Cook, Katherine L., Narayanan, Ramesh, Pierre, Joseph F., Makowski, Liza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8574993/
https://www.ncbi.nlm.nih.gov/pubmed/34161764
http://dx.doi.org/10.1016/j.celrep.2021.109285