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A new approach to decode DNA methylome and genomic variants simultaneously from double strand bisulfite sequencing

Genetic and epigenetic contributions to various diseases and biological processes have been well-recognized. However, simultaneous identification of single-nucleotide variants (SNVs) and DNA methylation levels from traditional bisulfite sequencing data is still challenging. Here, we develop double s...

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Detalles Bibliográficos
Autores principales: Liang, Jialong, Zhang, Kun, Yang, Jie, Li, Xianfeng, Li, Qinglan, Wang, Yan, Cai, Wanshi, Teng, Huajing, Sun, Zhongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575003/
https://www.ncbi.nlm.nih.gov/pubmed/34058751
http://dx.doi.org/10.1093/bib/bbab201