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A new approach to decode DNA methylome and genomic variants simultaneously from double strand bisulfite sequencing
Genetic and epigenetic contributions to various diseases and biological processes have been well-recognized. However, simultaneous identification of single-nucleotide variants (SNVs) and DNA methylation levels from traditional bisulfite sequencing data is still challenging. Here, we develop double s...
Autores principales: | Liang, Jialong, Zhang, Kun, Yang, Jie, Li, Xianfeng, Li, Qinglan, Wang, Yan, Cai, Wanshi, Teng, Huajing, Sun, Zhongsheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575003/ https://www.ncbi.nlm.nih.gov/pubmed/34058751 http://dx.doi.org/10.1093/bib/bbab201 |
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