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Atg39 selectively captures inner nuclear membrane into lumenal vesicles for delivery to the autophagosome

Mechanisms that turn over components of the nucleus and inner nuclear membrane (INM) remain to be fully defined. We explore how components of the INM are selected by a cytosolic autophagy apparatus through a transmembrane nuclear envelope–localized cargo adaptor, Atg39. A split-GFP reporter showed t...

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Detalles Bibliográficos
Autores principales: Chandra, Sunandini, Mannino, Philip J., Thaller, David J., Ader, Nicholas R., King, Megan C., Melia, Thomas J., Lusk, C. Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575018/
https://www.ncbi.nlm.nih.gov/pubmed/34714326
http://dx.doi.org/10.1083/jcb.202103030