Cargando…
Atg39 selectively captures inner nuclear membrane into lumenal vesicles for delivery to the autophagosome
Mechanisms that turn over components of the nucleus and inner nuclear membrane (INM) remain to be fully defined. We explore how components of the INM are selected by a cytosolic autophagy apparatus through a transmembrane nuclear envelope–localized cargo adaptor, Atg39. A split-GFP reporter showed t...
Autores principales: | Chandra, Sunandini, Mannino, Philip J., Thaller, David J., Ader, Nicholas R., King, Megan C., Melia, Thomas J., Lusk, C. Patrick |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575018/ https://www.ncbi.nlm.nih.gov/pubmed/34714326 http://dx.doi.org/10.1083/jcb.202103030 |
Ejemplares similares
-
ATG9 vesicles comprise the seed membrane of mammalian autophagosomes
por: Olivas, Taryn J., et al.
Publicado: (2023) -
ATG2 transports lipids to promote autophagosome biogenesis
por: Valverde, Diana P., et al.
Publicado: (2019) -
Atg4 in autophagosome biogenesis
por: Sánchez-Wandelmer, Jana, et al.
Publicado: (2017) -
Atg9 vesicles are an important membrane source during early steps of autophagosome formation
por: Yamamoto, Hayashi, et al.
Publicado: (2012) -
Atg1 kinase organizes autophagosome formation by phosphorylating Atg9
por: Papinski, Daniel, et al.
Publicado: (2014)