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PDB-wide identification of physiological hetero-oligomeric assemblies based on conserved quaternary structure geometry
An accurate understanding of biomolecular mechanisms and diseases requires information on protein quaternary structure (QS). A critical challenge in inferring QS information from crystallography data is distinguishing biological interfaces from fortuitous crystal-packing contacts. Here, we employ QS...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575123/ https://www.ncbi.nlm.nih.gov/pubmed/34520740 http://dx.doi.org/10.1016/j.str.2021.07.012 |