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PDB-wide identification of physiological hetero-oligomeric assemblies based on conserved quaternary structure geometry

An accurate understanding of biomolecular mechanisms and diseases requires information on protein quaternary structure (QS). A critical challenge in inferring QS information from crystallography data is distinguishing biological interfaces from fortuitous crystal-packing contacts. Here, we employ QS...

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Detalles Bibliográficos
Autores principales: Dey, Sucharita, Levy, Emmanuel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575123/
https://www.ncbi.nlm.nih.gov/pubmed/34520740
http://dx.doi.org/10.1016/j.str.2021.07.012