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Equipment-free detection of SARS-CoV-2 and Variants of Concern using Cas13

The COVID-19 pandemic, and the recent rise and widespread transmission of SARS-CoV-2 Variants of Concern (VOCs), have demonstrated the need for ubiquitous nucleic acid testing outside of centralized clinical laboratories. Here, we develop SHINEv2, a Cas13-based nucleic acid diagnostic that combines...

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Detalles Bibliográficos
Autores principales: Arizti-Sanz, Jon, Bradley, A’Doriann, Zhang, Yibin B., Boehm, Chloe K., Freije, Catherine A., Grunberg, Michelle E., Kosoko-Thoroddsen, Tinna-Solveig F., Welch, Nicole L., Pillai, Priya P., Mantena, Sreekar, Kim, Gaeun, Uwanibe, Jessica N., John, Oluwagboadurami G., Eromon, Philomena E., Kocher, Gregory, Gross, Robin, Lee, Justin S., Hensley, Lisa E., Happi, Christian T., Johnson, Jeremy, Sabeti, Pardis C., Myhrvold, Cameron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575147/
https://www.ncbi.nlm.nih.gov/pubmed/34751276
http://dx.doi.org/10.1101/2021.11.01.21265764