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Effect of Miricorilant, a Selective Glucocorticoid Receptor Modulator, on Olanzapine-Associated Weight Gain in Healthy Subjects: A Proof-of-Concept Study

PURPOSE: Antipsychotic medications, including olanzapine, are associated with substantial weight gain and metabolic disturbances. We sought to determine whether coadministration of miricorilant, a selective glucocorticoid receptor modulator, with olanzapine can ameliorate these effects. METHODS: Six...

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Detalles Bibliográficos
Autores principales: Hunt, Hazel J., Donaldson, Kirsteen, Strem, Mark, Tudor, Iulia Cristina, Sweet-Smith, Suzanne, Sidhu, Sharan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575171/
https://www.ncbi.nlm.nih.gov/pubmed/34369902
http://dx.doi.org/10.1097/JCP.0000000000001470