NKX2-1 re-expression induces cell death through apoptosis and necrosis in dedifferentiated thyroid carcinoma cells

NK2 homeobox 1 (NKX2-1) is a thyroid transcription factor essential for proper thyroid formation and maintaining its physiological function. In thyroid cancer, NKX2-1 expression decreases in parallel with declined differentiation. However, the molecular pathways and mechanisms connecting NKX2-1 to t...

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Detalles Bibliográficos
Autores principales: Ito, Yuko, Furuya, Fumihiko, Taki, Katsumi, Suzuki, Hideaki, Shimura, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575255/
https://www.ncbi.nlm.nih.gov/pubmed/34748583
http://dx.doi.org/10.1371/journal.pone.0259558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575255/
https://www.ncbi.nlm.nih.gov/pubmed/34748583
http://dx.doi.org/10.1371/journal.pone.0259558

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