Cargando…
NKX2-1 re-expression induces cell death through apoptosis and necrosis in dedifferentiated thyroid carcinoma cells
NK2 homeobox 1 (NKX2-1) is a thyroid transcription factor essential for proper thyroid formation and maintaining its physiological function. In thyroid cancer, NKX2-1 expression decreases in parallel with declined differentiation. However, the molecular pathways and mechanisms connecting NKX2-1 to t...
Autores principales: | Ito, Yuko, Furuya, Fumihiko, Taki, Katsumi, Suzuki, Hideaki, Shimura, Hiroki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575255/ https://www.ncbi.nlm.nih.gov/pubmed/34748583 http://dx.doi.org/10.1371/journal.pone.0259558 |
Ejemplares similares
-
Activation of the RhoB Signaling Pathway by Thyroid Hormone Receptor β in Thyroid Cancer Cells
por: Ichijo, Sayaka, et al.
Publicado: (2014) -
NKX2.5 is expressed in papillary thyroid carcinomas and regulates differentiation in thyroid cells
por: Penha, Ricardo Cortez Cardoso, et al.
Publicado: (2018) -
Possible Association Between Thyroid Nodule Formation and Developmental Alterations in the Pituitary–Thyroid Hormone Axis in Children and Adolescents: The Fukushima Health Management Survey
por: Suzuki, Satoshi, et al.
Publicado: (2022) -
Nevirapine inhibits migration and invasion in dedifferentiated thyroid cancer cells
por: Shang, Hongxia, et al.
Publicado: (2019) -
Identification of an immune-related signature indicating the dedifferentiation of thyroid cells
por: Wang, Xuemin, et al.
Publicado: (2021)