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Predicting novel candidate human obesity genes and their site of action by systematic functional screening in Drosophila

The discovery of human obesity-associated genes can reveal new mechanisms to target for weight loss therapy. Genetic studies of obese individuals and the analysis of rare genetic variants can identify novel obesity-associated genes. However, establishing a functional relationship between these candi...

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Detalles Bibliográficos
Autores principales: Agrawal, Neha, Lawler, Katherine, Davidson, Catherine M., Keogh, Julia M., Legg, Robert, Barroso, Inês, Farooqi, I. Sadaf, Brand, Andrea H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575313/
https://www.ncbi.nlm.nih.gov/pubmed/34748544
http://dx.doi.org/10.1371/journal.pbio.3001255