Cargando…
Predicting novel candidate human obesity genes and their site of action by systematic functional screening in Drosophila
The discovery of human obesity-associated genes can reveal new mechanisms to target for weight loss therapy. Genetic studies of obese individuals and the analysis of rare genetic variants can identify novel obesity-associated genes. However, establishing a functional relationship between these candi...
Autores principales: | Agrawal, Neha, Lawler, Katherine, Davidson, Catherine M., Keogh, Julia M., Legg, Robert, Barroso, Inês, Farooqi, I. Sadaf, Brand, Andrea H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575313/ https://www.ncbi.nlm.nih.gov/pubmed/34748544 http://dx.doi.org/10.1371/journal.pbio.3001255 |
Ejemplares similares
-
Genetic architecture of human thinness compared to severe obesity
por: Riveros-McKay, Fernando, et al.
Publicado: (2019) -
Obesity and thinness: insights from genetics
por: Farooqi, Sadaf
Publicado: (2023) -
Leptin-Mediated Changes in the Human Metabolome
por: Lawler, Katherine, et al.
Publicado: (2020) -
Obesity Due to Steroid Receptor Coactivator-1 Deficiency Is Associated With Endocrine and Metabolic Abnormalities
por: Cacciottolo, Tessa M, et al.
Publicado: (2022) -
MicroRNA-7 regulates melanocortin circuits involved in mammalian energy homeostasis
por: LaPierre, Mary P., et al.
Publicado: (2022)