Discovery of Camellia sinensis catechins as SARS-CoV-2 3CL protease inhibitors through molecular docking, intra and extra cellular assays

BACKGROUND AND PURPOSE: Previous studies suggest that major Camellia sinensis (tea) catechins can inhibit 3-chymotrypsin-like cysteine protease (3CLpro), inspiring us to study 3CLpro inhibition of the recently discovered catechins from tea by our group. METHODS: Autodock was used to dock 3CLpro and...

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Detalles Bibliográficos
Autores principales: Liu, Shi-Yu, Wang, Wei, Ke, Jia-Ping, Zhang, Peng, Chu, Gang-Xiu, Bao, Guan-Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier GmbH. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575542/
https://www.ncbi.nlm.nih.gov/pubmed/34799184
http://dx.doi.org/10.1016/j.phymed.2021.153853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575542/
https://www.ncbi.nlm.nih.gov/pubmed/34799184
http://dx.doi.org/10.1016/j.phymed.2021.153853

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