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Protective Effect of Uric Acid on ox-LDL-Induced HUVECs Injury via Keap1-Nrf2-ARE Pathway

Uric acid is an effective antioxidant. Oxidized low-density lipoprotein (ox-LDL) is derived from circulating LDL and promotes atherosclerosis. The Keap1-Nrf2-ARE pathway is a key body pathway involved in protection against internal and external oxidative damages. The role of uric acid on vascular en...

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Detalles Bibliográficos
Autores principales: Lin, Yajuan, Xie, Yunpeng, Hao, Zhujing, Bi, Hailian, Liu, Yang, Yang, Xiaolei, Xia, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575640/
https://www.ncbi.nlm.nih.gov/pubmed/34761008
http://dx.doi.org/10.1155/2021/5151168