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Characterization of subcellular localization of eukaryotic clamp loader/unloader and its regulatory mechanism
Proliferating cell nuclear antigen (PCNA) plays a critical role as a processivity clamp for eukaryotic DNA polymerases and a binding platform for many DNA replication and repair proteins. The enzymatic activities of PCNA loading and unloading have been studied extensively in vitro. However, the subc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575788/ https://www.ncbi.nlm.nih.gov/pubmed/34751190 http://dx.doi.org/10.1038/s41598-021-01336-w |