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Characterization of subcellular localization of eukaryotic clamp loader/unloader and its regulatory mechanism

Proliferating cell nuclear antigen (PCNA) plays a critical role as a processivity clamp for eukaryotic DNA polymerases and a binding platform for many DNA replication and repair proteins. The enzymatic activities of PCNA loading and unloading have been studied extensively in vitro. However, the subc...

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Detalles Bibliográficos
Autores principales: Park, Su Hyung, Kim, Seong-jung, Myung, Kyungjae, Lee, Kyoo-young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575788/
https://www.ncbi.nlm.nih.gov/pubmed/34751190
http://dx.doi.org/10.1038/s41598-021-01336-w