Metformin attenuates hypothalamic inflammation via downregulation of RIPK1-independent microglial necroptosis in diet-induced obese mice

Necroptosis, a form of programmed cell death, accounts for many inflammations in a wide range of diseases. Diet-induced obesity is manifested by low-grade inflammation in the mediobasal hypothalamus (MBH), and microglia are implicated as critical responsive components for this process. Here, we demo...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xuan, Cai, You, Luo, Jiao, Ding, Jingyun, Yao, Guojun, Xiao, Xiaohua, Tang, Yizhe, Liang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575871/
https://www.ncbi.nlm.nih.gov/pubmed/34750365
http://dx.doi.org/10.1038/s41420-021-00732-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575871/
https://www.ncbi.nlm.nih.gov/pubmed/34750365
http://dx.doi.org/10.1038/s41420-021-00732-5

Ejemplares similares