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Enzymatic ligation of an antibody and arginine 9 peptide for efficient and cell-specific siRNA delivery
A fusion protein comprising an antibody and a cationic peptide, such as arginine-9 (R9), is a candidate molecule for efficient and cell-specific delivery of siRNA into cells in order to reduce the side effects of nucleic acid drugs. However, their expression in bacterial hosts, required for their de...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575896/ https://www.ncbi.nlm.nih.gov/pubmed/34750461 http://dx.doi.org/10.1038/s41598-021-01331-1 |