MMAB promotes negative feedback control of cholesterol homeostasis

Intricate regulatory networks govern the net balance of cholesterol biosynthesis, uptake and efflux; however, the mechanisms surrounding cholesterol homeostasis remain incompletely understood. Here, we develop an integrative genomic strategy to detect regulators of LDLR activity and identify 250 gen...

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Detalles Bibliográficos
Autores principales: Goedeke, Leigh, Canfrán-Duque, Alberto, Rotllan, Noemi, Chaube, Balkrishna, Thompson, Bonne M., Lee, Richard G., Cline, Gary W., McDonald, Jeffrey G., Shulman, Gerald I., Lasunción, Miguel A., Suárez, Yajaira, Fernández-Hernando, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575900/
https://www.ncbi.nlm.nih.gov/pubmed/34750386
http://dx.doi.org/10.1038/s41467-021-26787-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575900/
https://www.ncbi.nlm.nih.gov/pubmed/34750386
http://dx.doi.org/10.1038/s41467-021-26787-7

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