TCP1 increases drug resistance in acute myeloid leukemia by suppressing autophagy via activating AKT/mTOR signaling

T-complex protein 1 (TCP1) is one of the subunits of chaperonin-containing T complex (CCT), which is involved in protein folding, cell proliferation, apoptosis, cell cycle regulation, and drug resistance. Investigations have demonstrated that TCP1 is a factor being responsible for drug resistance in...

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Detalles Bibliográficos
Autores principales: Chen, Xiaofang, Chen, Xianling, Huang, Yiping, Lin, Jia, Wu, Yong, Chen, Yuanzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575913/
https://www.ncbi.nlm.nih.gov/pubmed/34750375
http://dx.doi.org/10.1038/s41419-021-04336-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575913/
https://www.ncbi.nlm.nih.gov/pubmed/34750375
http://dx.doi.org/10.1038/s41419-021-04336-w

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