Adipose MDM2 regulates systemic insulin sensitivity

The intimate association between obesity and type II diabetes urges for a deeper understanding of adipocyte function. We and others have previously delineated a role for the tumor suppressor p53 in adipocyte biology. Here, we show that mice haploinsufficient for MDM2, a key regulator of p53, in thei...

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Detalles Bibliográficos
Autores principales: Hallenborg, Philip, Jensen, Benjamin Anderschou Holbech, Fjære, Even, Petersen, Rasmus Koefoed, Belmaâti, Mohammed-Samir, Rasmussen, Sarah Søndergård, Gunnarsson, Jon Petur, Lauritzen, Pernille, Cheng, Kenneth King Yip, Hermansson, Martin, Sonne, Si Brask, Ejsing, Christer S., Xu, Aimin, Kratchmarova, Irina, Krüger, Marcus, Madsen, Lise, Kristiansen, Karsten, Blagoev, Blagoy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575914/
https://www.ncbi.nlm.nih.gov/pubmed/34750429
http://dx.doi.org/10.1038/s41598-021-01240-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575914/
https://www.ncbi.nlm.nih.gov/pubmed/34750429
http://dx.doi.org/10.1038/s41598-021-01240-3

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