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RelA/MicroRNA-30a/NLRP3 signal axis is involved in rheumatoid arthritis via regulating NLRP3 inflammasome in macrophages

NLRP3 inflammasome plays an important role in the pathogenesis of rheumatoid arthritis (RA). However, the post-transcriptional regulation of NLRP3 expression by miRNA in synovial macrophages is still not well understood. The aim of the study is to elucidate the mechanisms of RA with the focus on miR...

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Detalles Bibliográficos
Autores principales: Yang, Qiudong, Zhao, Wenhua, Chen, Yuyi, Chen, Yue, Shi, Jiali, Qin, Ran, Wang, Hua, Wang, Ruixia, Yuan, Hua, Sun, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575917/
https://www.ncbi.nlm.nih.gov/pubmed/34750358
http://dx.doi.org/10.1038/s41419-021-04349-5