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Incorporation of apolipoprotein E into HBV–HCV subviral envelope particles to improve the hepatitis vaccine strategy

Hepatitis C is a major threat to public health for which an effective treatment is available, but a prophylactic vaccine is still needed to control this disease. We designed a vaccine based on chimeric HBV–HCV envelope proteins forming subviral particles (SVPs) that induce neutralizing antibodies ag...

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Detalles Bibliográficos
Autores principales: Gomez-Escobar, Elsa, Burlaud-Gaillard, Julien, Visdeloup, Clara, Ribeiro E Silva, Adeline, Coutant, Pauline, Roingeard, Philippe, Beaumont, Elodie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575973/
https://www.ncbi.nlm.nih.gov/pubmed/34750487
http://dx.doi.org/10.1038/s41598-021-01428-7