A potent truncated form of human soluble CR1 is protective in a mouse model of renal ischemia–reperfusion injury

The complement system is a potent mediator of ischemia–reperfusion injury (IRI), which detrimentally affects the function and survival of transplanted kidneys. Human complement receptor 1 (HuCR1) is an integral membrane protein that inhibits complement activation by blocking the convertases that act...

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Detalles Bibliográficos
Autores principales: Bongoni, Anjan K., Vikstrom, Ingela B., McRae, Jennifer L., Salvaris, Evelyn J., Fisicaro, Nella, Pearse, Martin J., Wymann, Sandra, Rowe, Tony, Morelli, Adriana Baz, Hardy, Matthew P., Cowan, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575974/
https://www.ncbi.nlm.nih.gov/pubmed/34750424
http://dx.doi.org/10.1038/s41598-021-01423-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575974/
https://www.ncbi.nlm.nih.gov/pubmed/34750424
http://dx.doi.org/10.1038/s41598-021-01423-y

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