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Albino mice with the point mutation at the tyrosinase locus show high cholesterol diet-induced NASH susceptibility

Non-alcoholic fatty liver disease (NAFLD) constitutes a metabolic disorder with high worldwide prevalence and increasing incidence. The inflammatory progressive state, non-alcoholic steatohepatitis (NASH), leads to liver fibrosis and carcinogenesis. Here, we evaluated whether tyrosinase mutation und...

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Detalles Bibliográficos
Autores principales: Kulathunga, Kaushalya, Wakimoto, Arata, Hiraishi, Yukiko, Yadav, Manoj Kumar, Gentleman, Kyle, Warabi, Eiji, Sakasai, Tomoki, Miwa, Yoshihiro, Mizuno, Seiya, Takahashi, Satoru, Hamada, Michito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576022/
https://www.ncbi.nlm.nih.gov/pubmed/34750345
http://dx.doi.org/10.1038/s41598-021-00501-5