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HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma

Lung adenocarcinoma is one of the most frequent tumor subtypes, involving changes in a variety of oncogenes and tumor suppressor genes. Hydroxysteroid 17-Beta Dehydrogenase 6 (HSD17B6) could synthetize dihydrotestosterone, abnormal levels of which are associated with progression of multiple tumors....

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Detalles Bibliográficos
Autores principales: Tian, Tian, Hong, Fu, Wang, Zhiwen, Hu, Jiaru, Chen, Ni, Lv, Lei, Yi, Qiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576029/
https://www.ncbi.nlm.nih.gov/pubmed/34750355
http://dx.doi.org/10.1038/s41420-021-00737-0