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Immunogenic and efficacious SARS-CoV-2 vaccine based on resistin-trimerized spike antigen SmT1 and SLA archaeosome adjuvant

The huge worldwide demand for vaccines targeting SARS-CoV-2 has necessitated the continued development of novel improved formulations capable of reducing the burden of the COVID-19 pandemic. Herein, we evaluated novel protein subunit vaccine formulations containing a resistin-trimerized spike antige...

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Detalles Bibliográficos
Autores principales: Akache, Bassel, Renner, Tyler M., Tran, Anh, Deschatelets, Lise, Dudani, Renu, Harrison, Blair A., Duque, Diana, Haukenfrers, Julie, Rossotti, Martin A., Gaudreault, Francis, Hemraz, Usha D., Lam, Edmond, Régnier, Sophie, Chen, Wangxue, Gervais, Christian, Stuible, Matthew, Krishnan, Lakshmi, Durocher, Yves, McCluskie, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576046/
https://www.ncbi.nlm.nih.gov/pubmed/34750472
http://dx.doi.org/10.1038/s41598-021-01363-7